Opportunity Information: Apply for HRSA 21 068
The HRSA SPNS grant opportunity "Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV - Evaluation Center" (HRSA-21-068) funds one organization to serve as the national Evaluation Center for a multi-year initiative focused on testing and learning from new approaches to HIV service delivery. The award is structured as a cooperative agreement, meaning the recipient is expected to work closely with HRSA and partner entities rather than operate independently. The project is designed to run for up to four years and supports a single recipient that will lead the evaluation effort for a set of pilot intervention sites funded through a separate, companion award known as the Coordinating Center and Technical Assistance provider (2iS CCTA; HRSA-21-076). In practical terms, this Evaluation Center is the initiative's measurement and learning hub, responsible for figuring out what works, for whom, under what conditions, and at what cost, then helping translate those findings into usable knowledge for the field.
The central purpose of the Evaluation Center is to apply an implementation science framework to evaluate pilot testing of innovative intervention strategies across four defined focus areas. Implementation science is emphasized because HRSA is not only interested in whether an intervention improves outcomes, but also how well it is adopted, integrated, and sustained in real-world Ryan White HIV/AIDS Program (RWHAP) settings. The Evaluation Center is expected to assess both implementation outcomes (such as uptake, acceptability, feasibility, fidelity, and integration into workflow) and client-level health outcomes associated with these interventions. The end goal is to produce credible, actionable findings that can guide broader dissemination and replication of successful strategies.
The initiative is built around up to 20 implementation sites that are RWHAP-funded recipients or subrecipients. These sites are expected to be subawarded and supported through the companion Coordinating Center award, and they will pilot one intervention strategy per site. The Evaluation Center must design and run a multi-site evaluation that includes two layers: first, a customized, site-specific evaluation component tailored to each implementation site's chosen intervention and context; and second, a set of cross-site evaluation components that are consistent across all sites. The cross-site work is meant to allow comparison and synthesis across diverse settings and interventions, and the notice highlights examples such as costing analyses and organizational assessments. This structure is intended to capture both local nuance and broader lessons that can be generalized or adapted to other RWHAP environments.
The four focus areas define the populations and service-delivery opportunity the pilots will target. Three are priority populations where HIV outcomes are often impacted by structural barriers and service gaps: (1) people with HIV who have substance use disorder, (2) LGBTQ youth with HIV, and (3) people with HIV who are currently incarcerated or who have a history of incarceration. The fourth focus area is an "area of opportunity" centered on improving HIV health outcomes through telehealth services, reflecting the growing role of remote care and technology-enabled engagement. The Evaluation Center's role is to evaluate implementation and outcomes across these focus areas, including how interventions are taken up in different organizational settings and how they affect engagement in care and other relevant HIV health indicators.
A defining feature of this opportunity is the required collaboration between the Evaluation Center (2iS EC) and the companion Coordinating Center (2iS CCTA). The Coordinating Center provides technical assistance to the implementation sites, helps develop tools and supports for intervention delivery, and plays a major role in organizing the initiative's on-the-ground activities. The Evaluation Center works alongside that effort by ensuring the pilots are evaluated in a rigorous, consistent way, while still allowing for site-specific adaptation. Importantly, the Evaluation Center's findings are positioned as the driver for dissemination plans: what is learned through the evaluation will shape how, and to what extent, replication tools developed by the Coordinating Center are packaged and shared for broader use.
Administratively, this is an FY2021 HRSA discretionary funding opportunity under CFDA 93.928, with one expected award. The funding opportunity was posted December 18, 2020, and originally closed March 8, 2021. Eligibility is listed broadly as "Others" with additional eligibility details referenced in the full announcement. The notice also notes this project is a competing continuation of earlier related SPNS initiatives (HRSA-17-044 and HRSA-17-049), signaling that it builds on prior SPNS work while updating focus areas and evaluation needs.
Overall, the opportunity is best understood as a national evaluation role within a coordinated demonstration initiative: multiple RWHAP sites pilot innovative strategies in four targeted areas, the Coordinating Center supports those sites with training and technical assistance, and the Evaluation Center designs and conducts the multi-site evaluation that determines the strength of evidence, implementation lessons, cost considerations, and the practical guidance needed to replicate successful approaches elsewhere.Apply for HRSA 21 068
- The Department of Health and Human Services, Health Resources and Services Administration in the health sector is offering a public funding opportunity titled "Using Innovative Intervention Strategies to Improve Health Outcomes among People with HIV - Evaluation Center" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.928.
- This funding opportunity was created on Dec 18, 2020.
- Applicants must submit their applications by Mar 08, 2021. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 1 candidate(s).
- Eligible applicants include: Others (see text field entitled Additional Information on Eligibility for clarification).
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