Opportunity Information: Apply for EP U3R 22 002
The Regional Ebola and Other Special Pathogen Treatment Centers (RESPTC) funding opportunity is a Department of Health and Human Services (HHS) cooperative agreement aimed at keeping the US health care system ready to manage Ebola and other high-consequence infectious diseases, often referred to as "special pathogens." The core goal is to sustain and strengthen preparedness across regions by putting the National Special Pathogen System of Care Strategy (NSPS of Care Strategy) into practice and by expanding the regional network of hospitals that can safely evaluate, isolate, and treat patients with these threats. In practical terms, the program is designed to ensure there are well-prepared, highly capable regional hubs that can support surrounding hospitals and health systems, so that a patient can be rapidly cared for without overwhelming any single facility.
At the center of the program is the idea that RESPTCs function as regional hubs for special pathogen readiness. These hubs are meant to be more than just hospitals with isolation rooms; they are intended to serve as operational and clinical resources for their broader region. That includes maintaining specialized clinical capability, supporting infection prevention and control practices, assisting with patient management workflows, and helping coordinate readiness activities among regional health care partners. A key piece is surge mitigation: if multiple facilities face demand at once, the RESPTCs help reduce strain by supporting patient distribution and regional coordination, rather than leaving each hospital to manage a high-risk situation in isolation.
The NOFO is structured in two parts that reflect both continuity and expansion. Under Part A, HHS provides direct funding to the ten health care facilities already designated as Regional Ebola and Other Special Pathogen Treatment Centers, with the intent of sustaining and improving their existing capabilities and ensuring they remain ready to respond as regional anchors. Under Part B, HHS plans to select three additional RESPTCs, expanding the national footprint and strengthening regional coverage. The expansion is described as using a "hub-and-spoke" model, where the RESPTC serves as the hub supporting a network of partner facilities (spokes) that can identify and stabilize suspected cases, coordinate transfers when needed, and follow consistent regional protocols.
Administratively, this opportunity is categorized as a discretionary grant program using a cooperative agreement mechanism, which typically signals substantial federal involvement beyond what is seen in a standard grant. The funding activity category is Disaster Prevention and Relief, reflecting the preparedness and response orientation of the work. The issuing office is HHS under the Assistant Secretary for Preparedness and Response (ASPR), an agency component that focuses on national readiness for public health emergencies and medical disasters.
The opportunity is identified by Funding Opportunity Number EP U3R 22 002 and CFDA (now often referenced as Assistance Listing) number 93.817. Eligible applicants include state governments, county governments, city or township governments, and other entities as specified in the full eligibility language referenced in the notice. The posting lists an award ceiling of $1,200,000 and an expected 10 awards, aligning with the continuing support for the existing ten RESPTCs described in Part A (while Part B describes an additional selection of three new centers as part of the overall program approach). The notice was created on August 24, 2022, with an original closing date of September 22, 2022.
Overall, the opportunity is about maintaining a nationally coordinated, regionally executed system for managing rare but high-impact infectious disease events. It emphasizes real-world operational readiness: ensuring designated regional centers remain capable of safely delivering care, supporting surrounding facilities with expertise and coordination, and preventing localized health system overload by managing patient distribution and regional response planning through a structured hub-and-spoke network.Apply for EP U3R 22 002
- The Department of Health and Human Services, Assistant Secretary for Preparedness and Response in the disaster prevention and relief sector is offering a public funding opportunity titled "Regional Ebola and Other Special Pathogen Treatment Centers" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.817.
- This funding opportunity was created on Aug 24, 2022.
- Applicants must submit their applications by Sep 22, 2022 No Explanation. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $1,200,000.00 in funding.
- The number of recipients for this funding is limited to 10 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Others (see text field entitled Additional Information on Eligibility for clarification).
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Frequently Asked Questions (FAQs)
1) What is the Regional Ebola and Other Special Pathogen Treatment Centers (RESPTC) funding opportunity?
RESPTC is a Department of Health and Human Services (HHS) cooperative agreement funding opportunity focused on keeping the U.S. health care system prepared to evaluate, isolate, and treat Ebola and other high-consequence infectious diseases (often called "special pathogens"). The program supports a nationally coordinated, regionally executed approach to readiness.
2) What is the main goal of this funding opportunity?
The core goal is to sustain and strengthen regional preparedness for special pathogens by putting the National Special Pathogen System of Care Strategy (NSPS of Care Strategy) into practice and expanding the regional network of hospitals that can safely manage these threats. The intent is to ensure rapid, safe patient care without overwhelming a single facility.
3) What are "special pathogens" in the context of this opportunity?
In this notice, "special pathogens" refers to Ebola and other high-consequence infectious diseases that require specialized readiness, including the ability to safely evaluate, isolate, and treat patients while protecting health care workers and maintaining operational coordination across a region.
4) How are RESPTCs expected to function within a region?
RESPTCs are intended to function as regional hubs for special pathogen readiness. They are not only treatment sites; they are also operational and clinical resources for surrounding hospitals and health systems. This includes supporting infection prevention and control practices, assisting with patient management workflows, and helping coordinate readiness activities among regional health care partners.
5) What does the "hub-and-spoke" model mean in this program?
The program describes a hub-and-spoke model where the RESPTC serves as the hub and partner facilities serve as spokes. In this structure, partner facilities can identify and stabilize suspected cases, coordinate transfers when needed, and follow consistent regional protocols supported by the hub.
6) What is "surge mitigation" and why is it emphasized?
Surge mitigation refers to reducing strain when multiple facilities face demand at the same time. The opportunity emphasizes that RESPTCs should help prevent localized overload by supporting patient distribution and regional coordination, rather than having each hospital manage high-risk situations on its own.
7) Who is issuing this funding opportunity?
The issuing office is the Department of Health and Human Services (HHS), through the Assistant Secretary for Preparedness and Response (ASPR), which focuses on national readiness for public health emergencies and medical disasters.
8) What type of funding mechanism is used?
This opportunity uses a cooperative agreement mechanism. The notice characterizes it as a discretionary grant program under a cooperative agreement, which typically indicates substantial federal involvement compared with a standard grant.
9) What is the funding activity category for this opportunity?
The funding activity category is Disaster Prevention and Relief, reflecting the preparedness and response focus of the work.
10) What is the Funding Opportunity Number and Assistance Listing (CFDA) number?
The Funding Opportunity Number is EP U3R 22 002. The CFDA (Assistance Listing) number is 93.817.
11) Who is eligible to apply based on the information provided?
Eligible applicants include state governments, county governments, city or township governments, and other entities as specified in the full eligibility language referenced in the notice.
12) How is the NOFO structured (Part A vs. Part B)?
The notice is structured in two parts:
- Part A: Direct funding to the ten health care facilities already designated as Regional Ebola and Other Special Pathogen Treatment Centers, to sustain and improve existing capabilities and maintain readiness as regional anchors.
- Part B: Selection of three additional RESPTCs to expand national footprint and strengthen regional coverage using the hub-and-spoke model.
13) How many awards are expected?
The posting lists an expected 10 awards, aligning with continued support for the existing ten RESPTCs described in Part A. The notice also describes an additional selection of three new centers under Part B as part of the overall program approach.
14) What is the maximum (ceiling) award amount listed?
The posting lists an award ceiling of $1,200,000.
15) When was the notice created and when did it close?
The notice was created on August 24, 2022, with an original closing date of September 22, 2022.
16) What kinds of capabilities are RESPTCs expected to sustain or strengthen?
Based on the description provided, RESPTCs are expected to maintain specialized clinical capability; support infection prevention and control practices; assist with patient management workflows; and coordinate readiness activities among regional health care partners, with an emphasis on operational readiness and regional coordination.
17) How does this opportunity help avoid overwhelming a single facility?
The opportunity emphasizes regional coordination and patient distribution through designated hubs (RESPTCs). By acting as regional anchors and coordinating with partner facilities, RESPTCs help ensure a patient can be rapidly cared for while preventing localized health system overload during high-consequence infectious disease events.
18) What is the broader purpose of creating or expanding a regional network?
The broader purpose is to maintain a nationally coordinated system that is executed regionally, ensuring consistent protocols and readiness across multiple facilities. This network approach supports safe evaluation, isolation, and treatment while strengthening coordination during rare but high-impact infectious disease events.
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