Opportunity Information: Apply for RFA MD 18 004
The National Institutes of Health (NIH) funding opportunity RFA-MD-18-004 is an R01 research grant focused on reducing HIV/AIDS disparities affecting women in the United States. The core goal is to support research that helps explain why HIV prevention, diagnosis, and treatment outcomes differ by race/ethnicity, geography, and socioeconomic status among US women, and to test practical ways to close those gaps. The announcement is broadly aimed at health services research, intervention research, and implementation research, meaning it is interested not only in whether an approach works, but also how to deliver effective approaches in real-world settings and systems of care.
Projects under this opportunity can address any point along the HIV continuum relevant to women, including prevention (such as uptake and adherence to preventive strategies, engagement with prevention services, or barriers to risk-reduction resources), screening and diagnosis (such as access to testing, timeliness of diagnosis, linkage to care after diagnosis, and factors that influence missed opportunities for detection), and treatment (including retention in care, antiretroviral therapy initiation and adherence, viral suppression, and broader care delivery issues). The emphasis on disparities indicates that proposals should center the unequal burdens and outcomes experienced by groups of women who are historically underserved or disproportionately affected, and should be designed to produce knowledge that can realistically inform programs, policies, clinical workflows, or community-based service delivery.
The opportunity allows a range of study designs and data sources. Applicants may propose primary data collection, which could include recruiting participants, collecting new clinical or behavioral data, or implementing and evaluating interventions in clinics or community settings. Applicants may also use secondary analyses of existing datasets, which could involve analyzing surveillance data, electronic health records, claims data, cohort studies, or other established data resources to identify drivers of disparities or to evaluate real-world service patterns and outcomes. The R01 mechanism typically supports substantial, multi-year research projects, and this specific announcement also notes that applications may either include clinical trial(s) or not, meaning both interventional studies and non-trial research are within scope as long as they are responsive to the disparity-reduction focus.
Eligibility is intentionally broad and includes many types of organizations that might be positioned to conduct or partner on disparity-focused HIV research involving women. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled colleges and universities; private institutions of higher education; federally recognized Native American tribal governments; public housing authorities/Indian housing authorities; tribal organizations that are not federally recognized; nonprofits with and without 501(c)(3) status (as long as they are not institutions of higher education in those categories); for-profit organizations (other than small businesses); small businesses; and other entities. The announcement also highlights additional eligible applicant types such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, regional organizations, eligible federal agencies, and US territories or possessions. This wide net reflects the reality that effective HIV disparity work often depends on partnerships across academic, clinical, public health, and community systems.
At the same time, there are important limits on foreign participation. Non-domestic (non-US) entities and non-domestic components of US organizations are not eligible to apply as the applicant organization. However, foreign components are allowed as defined by the NIH Grants Policy Statement, meaning a US-based applicant may include certain international elements in the project when justified and compliant with NIH policy, but the lead applicant organization must be domestic.
Key administrative details included in the source information are that this is a discretionary grant opportunity in the health category under CFDA 93.307, administered by NIH, with an original closing date of April 30, 2018. The listed award ceiling is $350,000. The opportunity was created on December 7, 2017.Apply for RFA MD 18 004
- The National Institutes of Health in the health sector is offering a public funding opportunity titled "Prevention and Treatment Research to Address HIV/AIDS Disparities in Women in the US (R01-Accepting applications that either propose or do not propose clinical trial(s))" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.307.
- This funding opportunity was created on 2017-12-07.
- Applicants must submit their applications by 2018-04-30. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $350,000.00 in funding.
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.
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Frequently Asked Questions (FAQ)
What is the NIH funding opportunity RFA-MD-18-004 about?
RFA-MD-18-004 is an NIH R01 research grant opportunity focused on reducing HIV/AIDS disparities affecting women in the United States. It supports research that explains why HIV prevention, diagnosis, and treatment outcomes differ by race/ethnicity, geography, and socioeconomic status among US women, and that tests practical ways to reduce those gaps in real-world settings.
What is the main goal of this opportunity?
The core goal is to fund research that both (1) helps explain the drivers of HIV-related disparities among women in the US and (2) evaluates approaches that can realistically improve equity in prevention, diagnosis, and treatment outcomes.
What types of research does the announcement emphasize?
The opportunity is broadly aimed at health services research, intervention research, and implementation research. That means it is interested not only in whether an approach works, but also how effective approaches can be delivered in real-world systems of care (clinical, public health, and community-based settings).
Is the focus limited to clinical interventions, or can it include systems and service delivery research?
It can include systems and service delivery research. The announcement specifically highlights health services and implementation perspectives, and it encourages research designed to inform programs, policies, clinical workflows, or community-based service delivery related to HIV disparities among women.
What populations should proposals center on?
Proposals should center on women in the United States who experience unequal HIV burdens and outcomes, particularly groups that are historically underserved or disproportionately affected. The disparities focus specifically mentions differences by race/ethnicity, geography, and socioeconomic status.
What points along the HIV continuum are in scope?
Projects may address any point along the HIV continuum relevant to women, including prevention, screening and diagnosis, and treatment.
What kinds of HIV prevention topics are considered responsive?
Prevention-related topics can include uptake and adherence to preventive strategies, engagement with prevention services, and barriers to accessing risk-reduction resources, as long as the work is tied to understanding and/or reducing disparities among women in the US.
What kinds of screening and diagnosis topics are considered responsive?
Screening and diagnosis topics may include access to HIV testing, timeliness of diagnosis, linkage to care after diagnosis, and factors that contribute to missed opportunities for detection, with an emphasis on disparity drivers and disparity reduction among women.
What kinds of treatment and care topics are considered responsive?
Treatment topics can include retention in care, antiretroviral therapy initiation and adherence, viral suppression, and broader HIV care delivery issues, particularly where they relate to unequal outcomes and practical strategies to improve equity for women.
Does this opportunity require applicants to run a clinical trial?
No. Applications may include clinical trial(s) or may be non-trial research. Both are within scope if they are responsive to the disparity-reduction focus for women in the US.
What study designs and data sources are allowed?
The opportunity allows a range of study designs and data sources, including both primary data collection and secondary analyses of existing datasets.
What counts as primary data collection under this opportunity?
Primary data collection can include recruiting participants, collecting new clinical or behavioral data, and implementing and evaluating interventions in clinics or community settings.
What counts as secondary data analysis under this opportunity?
Secondary analysis can include using existing data sources such as surveillance data, electronic health records, claims data, cohort studies, or other established datasets to identify drivers of disparities or evaluate real-world service patterns and outcomes.
What is the funding mechanism for this grant?
The funding mechanism is an NIH R01 research project grant, which typically supports substantial, multi-year research projects.
What is the maximum award amount (award ceiling) listed for this opportunity?
The listed award ceiling is $350,000.
Who is eligible to apply?
Eligibility is broad and includes many domestic (US-based) organization types, including various levels of government, educational institutions, tribal entities, nonprofits, for-profits, and small businesses, among others.
Which government entities are eligible applicants?
Eligible government applicants include state governments; county governments; city or township governments; special district governments; independent school districts; and US territories or possessions. The opportunity also lists eligible federal agencies.
Which higher education institutions are eligible?
Eligible institutions include public and state-controlled colleges and universities and private institutions of higher education. The announcement also highlights specific institution types such as HBCUs, Hispanic-serving Institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and AANAPISIs.
Are tribal governments and tribal organizations eligible?
Yes. Federally recognized Native American tribal governments are eligible, and tribal organizations that are not federally recognized are also listed as eligible applicants.
Are nonprofits eligible to apply?
Yes. The opportunity includes nonprofits with and without 501(c)(3) status (in the categories specified), reflecting the role community and service organizations can play in disparity-focused HIV research involving women.
Are for-profit organizations and small businesses eligible?
Yes. For-profit organizations (other than small businesses) and small businesses are both listed as eligible applicants.
Are faith-based and community-based organizations eligible?
Yes. The announcement explicitly highlights faith-based or community-based organizations as eligible applicant types.
Can non-US (foreign) organizations apply as the lead applicant?
No. Non-domestic (non-US) entities and non-domestic components of US organizations are not eligible to apply as the applicant organization. The lead applicant organization must be domestic.
Are any international (foreign) components allowed within an otherwise US-led project?
Yes. Foreign components are allowed as defined by the NIH Grants Policy Statement. This means a US-based applicant may include certain international elements when justified and compliant with NIH policy, but the applicant organization itself must be domestic.
Which agency administers this grant opportunity?
The opportunity is administered by the National Institutes of Health (NIH).
What is the CFDA number and category for this opportunity?
The opportunity is listed under CFDA 93.307 in the health category.
What type of grant is this described as?
It is described as a discretionary grant opportunity.
What was the original closing date for applications?
The original closing date listed is April 30, 2018.
When was this opportunity created?
The opportunity was created on December 7, 2017.
What makes an application "responsive" to this announcement based on the description provided?
Based on the description provided, a responsive application should focus on reducing HIV/AIDS disparities affecting women in the US, explain why outcomes differ across race/ethnicity, geography, and socioeconomic status, and/or test practical approaches to close those gaps in real-world care and service settings.
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