Opportunity Information: Apply for CDC RFA CK20 2003
The CDC funding opportunity titled "Improving Clinical and Public Health Outcomes through National Partnerships to Prevent and Control Emerging and Re-Emerging Infectious Disease Threats" is designed to strengthen the nations ability to respond quickly and effectively to infectious disease threats like COVID-19 and other emerging or returning pathogens. It does this by partnering with organizations that sit close to the front lines of infection prevention and control, including groups representing clinicians, other healthcare professionals, healthcare systems, and institutions that play a direct role in controlling spread in the United States. The overall idea is to build and maintain practical infrastructure and relationships that can be activated rapidly during a public health emergency, so that CDC guidance and tools reach the people who need them and are implemented in real-world settings.
A key feature of this Notice of Funding Opportunity (NOFO) is that it establishes an "Approved-But-Unfunded" (ABU) list. In practice, that means the CDC is not necessarily committing to immediate funding for everyone selected under the announcement. Instead, the agency is pre-qualifying a roster of organizations that have been reviewed, approved, and can be funded quickly when a specific infectious disease threat emerges and funds become available. This approach is meant to reduce delays that can happen when new outbreaks require urgent action, allowing CDC to move faster by working through already-vetted national and regional partners. The NOFO also makes clear that proposals have to align tightly with the listed program activities; applications that focus on activities outside that scope are considered non-responsive and will not be reviewed.
The work supported under the umbrella cooperative agreement centers on five connected strategies. The first, "Disseminate and Adopt," focuses on helping CDC spread guidance, clinical guidelines, and best practices and ensuring they are actually taken up and implemented by healthcare and public health audiences. The second, "Inform and Adapt," is about two-way communication: partners help CDC refine, tailor, and adapt guidance and tools so they fit the needs of specific patient populations, clinical specialties, and workplace or industry sectors where risk and operational realities differ. The third, "Target and Train," emphasizes workforce engagement and training, with partners leading efforts to train frontline personnel and the broader workforce in CDC best practices, while also improving reach into higher-risk communities and workplaces where transmission may be harder to control. The fourth strategy, "Integrate and Extend," supports building cross-specialty and integrated networks for rapid information sharing, troubleshooting, and spreading promising practices, including the creation of rapid or "living" learning networks that can update approaches as evidence changes; it also stresses extending these networks to vulnerable and hard-to-reach populations. The fifth, "Evaluate and Improve," requires partners to measure whether these strategies are working by evaluating impact, tracking performance metrics tied to prevention and control, and using continuous improvement approaches to strengthen infection prevention programs over time.
Administratively, this is a discretionary cooperative agreement (meaning CDC expects substantial involvement and collaboration with recipients rather than a hands-off grant). It falls under the Department of Health and Human Services, Centers for Disease Control and Prevention, specifically NCEZID, and is associated with CFDA number 93.318. The eligible applicant pool is broad and includes many types of government entities (state, county, city/township, special districts), public and private institutions of higher education, tribal governments and tribal organizations, public housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (other than small businesses), small businesses, and other entities as allowed by the eligibility clarifications. The opportunity was created July 1, 2020, with an original application deadline of July 31, 2020 (11:59 p.m. Eastern for electronic submissions). The listing notes an expected 24 awards, and the award ceiling is shown as 0, which typically signals that award amounts may vary, may depend on available funding, or may be determined later based on the specific threat and response needs rather than being capped in the announcement.
Taken together, the NOFO is less about funding a single fixed project and more about building a ready-to-activate national partner network that can rapidly push out CDC guidance, adapt it to real settings, train and equip frontline workers, connect organizations into learning and response networks, and evaluate what is working so infection prevention and control improves during fast-moving public health threats.Apply for CDC RFA CK20 2003
- The Department of Health and Human Services, Centers for Disease Control - NCEZID in the health sector is offering a public funding opportunity titled "Improving Clinical and Public Health Outcomes through National Partnerships to Prevent and Control Emerging and Re-Emerging Infectious Disease Threats" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
- This funding opportunity was created on Jul 01, 2020.
- Applicants must submit their applications by Jul 31, 2020 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 24 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs)
What is the title of this CDC funding opportunity?
The funding opportunity is titled "Improving Clinical and Public Health Outcomes through National Partnerships to Prevent and Control Emerging and Re-Emerging Infectious Disease Threats."
What is the main purpose of this Notice of Funding Opportunity (NOFO)?
The purpose is to strengthen the United States' ability to respond quickly and effectively to infectious disease threats (such as COVID-19 and other emerging or re-emerging pathogens) by partnering with organizations close to the front lines of infection prevention and control.
What kind of approach is CDC using in this NOFO?
The NOFO focuses on building and maintaining practical infrastructure and relationships that can be rapidly activated during a public health emergency so CDC guidance and tools reach healthcare and public health audiences and are implemented in real-world settings.
What does "Approved-But-Unfunded" (ABU) mean in this NOFO?
Does being placed on the ABU list guarantee immediate funding?
No. The ABU structure indicates CDC is not necessarily committing to immediate funding for everyone selected. Funding may occur later when a specific threat emerges and funds become available.
Why is CDC establishing an ABU list?
The ABU list is designed to reduce delays during urgent outbreak responses by allowing CDC to work with already-vetted partners rather than starting a new vetting process during an emergency.
What happens if an application proposes activities outside the NOFO's stated scope?
The NOFO states that proposals must align tightly with the listed program activities. Applications focusing on activities outside that scope are considered non-responsive and will not be reviewed.
What type of award mechanism is this?
This is a discretionary cooperative agreement, which means CDC expects substantial involvement and collaboration with recipients (not a fully hands-off grant).
Which federal agency and CDC center are associated with this opportunity?
The opportunity is under the U.S. Department of Health and Human Services (HHS), Centers for Disease Control and Prevention (CDC), specifically NCEZID.
What is the CFDA number associated with this opportunity?
The CFDA number listed is 93.318.
Who is this NOFO intended to partner with?
It is designed to partner with organizations that sit close to the front lines of infection prevention and control, including groups representing clinicians, other healthcare professionals, healthcare systems, and institutions that play a direct role in controlling spread in the United States.
What are the five strategies supported under this cooperative agreement?
The work centers on five connected strategies: Disseminate and Adopt; Inform and Adapt; Target and Train; Integrate and Extend; and Evaluate and Improve.
What does the "Disseminate and Adopt" strategy involve?
It focuses on helping CDC spread guidance, clinical guidelines, and best practices, and supporting real-world uptake and implementation by healthcare and public health audiences.
What does the "Inform and Adapt" strategy involve?
It emphasizes two-way communication so partners can help CDC refine, tailor, and adapt guidance and tools to fit the needs of specific patient populations, clinical specialties, and workplace or industry sectors.
What does the "Target and Train" strategy involve?
It focuses on workforce engagement and training, with partners leading efforts to train frontline personnel and the broader workforce in CDC best practices, while improving reach into higher-risk communities and workplaces.
What does the "Integrate and Extend" strategy involve?
It supports building cross-specialty and integrated networks for rapid information sharing, troubleshooting, and spreading promising practices. It also includes creating rapid or "living" learning networks that can update approaches as evidence changes, and extending these networks to vulnerable and hard-to-reach populations.
What does the "Evaluate and Improve" strategy involve?
It requires partners to evaluate impact, track performance metrics tied to prevention and control, and use continuous improvement approaches to strengthen infection prevention programs over time.
How many awards are expected under this opportunity?
The listing notes an expected 24 awards.
What is the award ceiling for this NOFO?
The award ceiling is shown as 0, which typically signals that award amounts may vary, may depend on available funding, or may be determined later based on the specific threat and response needs rather than being capped in the announcement.
What types of organizations are eligible to apply?
The eligible applicant pool is broad and includes: state governments; county governments; city or township governments; special district governments; public and private institutions of higher education; tribal governments; tribal organizations; public housing authorities; nonprofits with or without 501(c)(3) status; for-profit organizations (other than small businesses); small businesses; and other entities as allowed by eligibility clarifications.
When was this opportunity created, and what was the original application deadline?
The opportunity was created July 1, 2020, and the original application deadline was July 31, 2020, at 11:59 p.m. Eastern Time for electronic submissions.
Is this NOFO meant to fund one fixed project?
No. The NOFO is described as less about funding a single fixed project and more about building a ready-to-activate national partner network that can rapidly disseminate and adapt CDC guidance, train and equip frontline workers, connect organizations into learning and response networks, and evaluate what is working during fast-moving public health threats.
What is the overall benefit of this cooperative agreement model during emergencies?
The model is intended to make response faster by relying on practical infrastructure and pre-established partnerships, so CDC guidance and tools can be pushed out, tailored, implemented, and improved quickly during emerging or re-emerging infectious disease threats.
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