Opportunity Information: Apply for CDC RFA CK20 2003

The CDC funding opportunity titled "Improving Clinical and Public Health Outcomes through National Partnerships to Prevent and Control Emerging and Re-Emerging Infectious Disease Threats" is designed to strengthen the nations ability to respond quickly and effectively to infectious disease threats like COVID-19 and other emerging or returning pathogens. It does this by partnering with organizations that sit close to the front lines of infection prevention and control, including groups representing clinicians, other healthcare professionals, healthcare systems, and institutions that play a direct role in controlling spread in the United States. The overall idea is to build and maintain practical infrastructure and relationships that can be activated rapidly during a public health emergency, so that CDC guidance and tools reach the people who need them and are implemented in real-world settings.

A key feature of this Notice of Funding Opportunity (NOFO) is that it establishes an "Approved-But-Unfunded" (ABU) list. In practice, that means the CDC is not necessarily committing to immediate funding for everyone selected under the announcement. Instead, the agency is pre-qualifying a roster of organizations that have been reviewed, approved, and can be funded quickly when a specific infectious disease threat emerges and funds become available. This approach is meant to reduce delays that can happen when new outbreaks require urgent action, allowing CDC to move faster by working through already-vetted national and regional partners. The NOFO also makes clear that proposals have to align tightly with the listed program activities; applications that focus on activities outside that scope are considered non-responsive and will not be reviewed.

The work supported under the umbrella cooperative agreement centers on five connected strategies. The first, "Disseminate and Adopt," focuses on helping CDC spread guidance, clinical guidelines, and best practices and ensuring they are actually taken up and implemented by healthcare and public health audiences. The second, "Inform and Adapt," is about two-way communication: partners help CDC refine, tailor, and adapt guidance and tools so they fit the needs of specific patient populations, clinical specialties, and workplace or industry sectors where risk and operational realities differ. The third, "Target and Train," emphasizes workforce engagement and training, with partners leading efforts to train frontline personnel and the broader workforce in CDC best practices, while also improving reach into higher-risk communities and workplaces where transmission may be harder to control. The fourth strategy, "Integrate and Extend," supports building cross-specialty and integrated networks for rapid information sharing, troubleshooting, and spreading promising practices, including the creation of rapid or "living" learning networks that can update approaches as evidence changes; it also stresses extending these networks to vulnerable and hard-to-reach populations. The fifth, "Evaluate and Improve," requires partners to measure whether these strategies are working by evaluating impact, tracking performance metrics tied to prevention and control, and using continuous improvement approaches to strengthen infection prevention programs over time.

Administratively, this is a discretionary cooperative agreement (meaning CDC expects substantial involvement and collaboration with recipients rather than a hands-off grant). It falls under the Department of Health and Human Services, Centers for Disease Control and Prevention, specifically NCEZID, and is associated with CFDA number 93.318. The eligible applicant pool is broad and includes many types of government entities (state, county, city/township, special districts), public and private institutions of higher education, tribal governments and tribal organizations, public housing authorities, nonprofits with or without 501(c)(3) status, for-profit organizations (other than small businesses), small businesses, and other entities as allowed by the eligibility clarifications. The opportunity was created July 1, 2020, with an original application deadline of July 31, 2020 (11:59 p.m. Eastern for electronic submissions). The listing notes an expected 24 awards, and the award ceiling is shown as 0, which typically signals that award amounts may vary, may depend on available funding, or may be determined later based on the specific threat and response needs rather than being capped in the announcement.

Taken together, the NOFO is less about funding a single fixed project and more about building a ready-to-activate national partner network that can rapidly push out CDC guidance, adapt it to real settings, train and equip frontline workers, connect organizations into learning and response networks, and evaluate what is working so infection prevention and control improves during fast-moving public health threats.

  • The Department of Health and Human Services, Centers for Disease Control - NCEZID in the health sector is offering a public funding opportunity titled "Improving Clinical and Public Health Outcomes through National Partnerships to Prevent and Control Emerging and Re-Emerging Infectious Disease Threats" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.318.
  • This funding opportunity was created on Jul 01, 2020.
  • Applicants must submit their applications by Jul 31, 2020 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • The number of recipients for this funding is limited to 24 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification), Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
Apply for CDC RFA CK20 2003

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